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ShareTop 5 Cryptos of the Week – September 28, 2026 | Weekly Top Gainers
The broader crypto market had a relatively modest week in terms of overall growth, but selected crypto assets once again delivered significantly stronger returns. Investor attention shifted toward interoperability, Layer-1 infrastructure, blockchain data services, and AI-related projects, allowing several altcoins to outperform the largest crypto assets.
Quant became the clear standout with an extraordinary triple-digit weekly increase, while Sei, Pyth Network, Artificial Superintelligence Alliance, and LayerZero also recorded strong gains. Below are the Top 5 Crypto Assets of the Week – September 28, 2026, ranked by their 7-day percentage gains, prices, and market capitalizations.
Market Overview – Bitcoin, Ethereum and Litecoin
The largest crypto assets experienced considerably more restrained price action than this week's leading altcoins. Bitcoin continued trading around the mid-$80,000 range, while Ethereum remained near $2,700 and Litecoin stayed around the mid-$50 level. Their comparatively modest weekly movements created a noticeable contrast with the double- and triple-digit gains generated by several smaller crypto assets.
Bitcoin (BTC)
Bitcoin was trading at approximately $85,000–$86,000 around September 28, maintaining much of the momentum generated during its recent recovery. BTC remained the dominant crypto asset by market capitalization, valued at roughly $1.7 trillion. Although Bitcoin did not match the percentage gains recorded by this week's leading altcoins, its ability to remain above $80,000 continued to support overall market confidence.
Ethereum (ETH)
Ethereum was trading at approximately $2,700, with its market capitalization remaining above $325 billion. ETH experienced relatively modest weekly movement compared with several smaller crypto assets, despite continued activity across decentralized finance, staking, Layer-2 networks, and smart contract applications. Ethereum's stability provided a supportive environment for infrastructure-related projects to attract additional capital.
Litecoin (LTC)
Litecoin continued trading around the mid-$50 range, recording considerably smaller percentage movements than the assets featured in this week's ranking. LTC remained relatively stable alongside Bitcoin and Ethereum, while stronger speculative activity shifted toward smaller Layer-1, interoperability, oracle, and AI-related crypto projects.
#1 Quant (QNT) – Weekly Gain 314%
Quant (QNT) became this week's strongest-performing crypto asset, recording an extraordinary 314% increase. Quant is a blockchain interoperability project best known for Overledger, technology designed to connect different blockchain networks and traditional systems while enabling applications to communicate across multiple distributed ledgers.
Potential reasons behind the price increase:
- Growing demand for blockchain interoperability solutions
- Increased market attention toward cross-chain infrastructure
- Renewed interest in enterprise blockchain connectivity
- Strong momentum-driven and speculative trading activity
- Rapid increase in trading volumes following QNT's initial rally
The exceptional 314% weekly increase placed QNT far ahead of every other asset in this week's ranking and made it the week's clear standout performer.
#2 Sei (SEI) – Weekly Gain 40%
Sei (SEI) secured second place with a 40% increase, bringing its price to approximately $0.07 and its market capitalization to $605 million. Sei is a Layer-1 blockchain designed specifically for high-performance trading and decentralized applications, with an emphasis on speed, scalability, and efficient transaction execution.
Potential reasons behind the price increase:
- Renewed demand for high-performance Layer-1 networks
- Growing activity across the Sei ecosystem
- Increased investor interest in trading-focused blockchain infrastructure
- Rising decentralized application activity
- Strong capital inflows following positive price momentum
These factors helped SEI substantially outperform the broader crypto market and secure second place this week.
#3 Pyth Network (PYTH) – Weekly Gain 29%
Pyth Network (PYTH) recorded a 29% increase, reaching approximately $0.07 with a market capitalization of $624 million. Pyth Network is a decentralized oracle protocol designed to provide blockchain applications with real-time financial market data, including prices for crypto assets, equities, commodities, and other financial instruments.
Potential reasons behind the price increase:
- Growing demand for decentralized oracle infrastructure
- Increased adoption of real-time blockchain data services
- Expansion of Pyth integrations across blockchain ecosystems
- Rising DeFi activity requiring reliable market data
- Renewed investor interest in blockchain infrastructure projects
Pyth Network's latest performance also marks a return to our weekly ranking after appearing among the Top 5 earlier in the year.
#4 Artificial Superintelligence Alliance (FET) – Weekly Gain 25%
Artificial Superintelligence Alliance (FET) posted a 25% increase, bringing its price to approximately $0.23 and its market capitalization to $531 million. FET is associated with the Artificial Superintelligence Alliance, an initiative combining decentralized AI technologies and blockchain infrastructure with the broader goal of developing an open ecosystem for artificial intelligence.
Potential reasons behind the price increase:
- Renewed investor interest in AI-related crypto projects
- Growing attention toward decentralized artificial intelligence
- Increased market focus on AI and blockchain integration
- Higher trading activity following positive price momentum
- Capital rotation toward technology-focused crypto narratives
The continued popularity of artificial intelligence as a blockchain narrative helped FET secure fourth place among this week's strongest performers.
#5 LayerZero (ZRO) – Weekly Gain 22%
LayerZero (ZRO) completes this week's Top 5 with a 22% increase, reaching approximately $1.44 and a market capitalization of $547 million. LayerZero is an interoperability protocol designed to enable applications and blockchain networks to communicate across different chains, supporting the development of omnichain applications and cross-chain infrastructure.
Potential reasons behind the price increase:
- Growing demand for cross-chain interoperability
- Increased adoption of omnichain applications
- Expansion of LayerZero integrations
- Renewed investor interest in blockchain infrastructure
- Higher trading volumes and positive price momentum
LayerZero's return to the weekly Top 5 reinforces the continued market interest in interoperability as blockchain ecosystems become increasingly interconnected.
Weekly Summary
The week ending September 28 demonstrated another significant contrast between modest broader-market growth and much stronger performance among selected altcoins. Bitcoin, Ethereum, and Litecoin recorded comparatively restrained movements, while infrastructure and technology-focused projects attracted substantial capital.
Quant dominated this week's ranking with a 314% increase, followed by Sei at 40%, Pyth Network at 29%, Artificial Superintelligence Alliance at 25%, and LayerZero at 22%. Interoperability, Layer-1 infrastructure, decentralized data, and artificial intelligence were among the strongest narratives represented in this week's Top 5.